Research Progress-Institute of Animal Science,Guangdong Academy of Agricultural Sciences(Fisheries Research Institute)

CN EN

Systematic microbiology and Synthetic Biology

The Research Direction

• Cellular network research
• High-throughput compound-genome analysis based on (Bar-Seq) technique
• CROSS-SPECIES BACTERIAL CONJUGATION system development

Research Results

• Barcode deletion strain collection.The barcode deletion strain library made it possible to monitor the population variation of all deletion strains in a mixed culture medium of all gene deletion strains. This makes it possible to screen the function of each gene under various environmental conditions.

• We developed two types of gene deletion strains collection, which enables experimental genetic interaction analysis by constructing ultra-efficient double deletion strains by joining.

• We have been working on the development of a highly efficient gene transfer method using junctions. We have been using F plasmid for gene transfer, but now we are using RP4 plasmid for genome size heterologous gene transfer.

• We have made it possible to experimentally produce very large amounts of information. We will use this information, along with a number of statistical analysis methods, to conduct research aimed at elucidating the fluctuating state of dynamic intracellular network structures due to environmental changes.

Team experts

Systematic microbiology and Synthetic Biology

Systematic microbiology and Synthetic Biology

Contact Information

Phone: 020-38818923
E-mail: lijiazhou@gdaas.cn